曾憲思，副教授，碩士生導(dǎo)師
學(xué) 歷：博士
專 業(yè)：環(huán)境生物學(xué)
辦公室：生物樓418
Email：zxs-2005@vip.163.com
教育經(jīng)歷
2005.09-2009.07 信陽(yáng)師范學(xué)院，學(xué)士
2009.09-2014.06 昆明理工大學(xué)，博士
工作經(jīng)歷
2014.07-至今 信陽(yáng)師范學(xué)院生命科學(xué)學(xué)院 講師、副教授
2017.08-2018.08 圣路易斯華盛頓大學(xué)醫(yī)學(xué)院 訪問(wèn)學(xué)者
社會(huì)兼職
美國(guó)神經(jīng)化學(xué)協(xié)會(huì)會(huì)員，Neurotoxicity Research等多個(gè)國(guó)際SCI期刊的審稿人。
教學(xué)情況
先后主講本科生《生物制藥工藝學(xué)》、《生物化學(xué)》、《藥物分析實(shí)驗(yàn)》和《專業(yè)英語(yǔ)》等課程，研究生《專業(yè)英語(yǔ)》課程。
研究領(lǐng)域
帕金森病的發(fā)病機(jī)制及硫氧還蛋白的神經(jīng)保護(hù)作用。
獲資助項(xiàng)目
主持國(guó)家自然科學(xué)基金青年項(xiàng)目、河南省科技攻關(guān)項(xiàng)目、河南省高等學(xué)校重點(diǎn)科研項(xiàng)目基礎(chǔ)研究項(xiàng)目、河南省高層次人才國(guó)際化培養(yǎng)項(xiàng)目和信陽(yáng)師范學(xué)院博士科研啟動(dòng)基金項(xiàng)目。
代表性論文
? co-first author，*Corresponding Author
Xian-Si Zeng?*, Wen-Shuo Geng?, Lei Chen and Jin-Jing Jia*. Thioredoxin as a Therapeutic Target in Cerebral
Ischemia. Current Pharmaceutical Design, 2018, 24 (25): 2986-2992. (IF=2.757，期刊約稿文章)
Xian-Si Zeng, Wen-Shuo Geng and Jin-Jing Jia*. Neurotoxin-Induced Animal Models of Parkinson Disease:
Pathogenic Mechanism and Assessment. ASN Neuro. 2018, 10:1759091418777438. (IF=3.03，美國(guó)神經(jīng)化學(xué)協(xié)會(huì)官方
期刊約稿文章)
Xian-Si Zeng*, Wen-Shuo Geng, Jin-Jing Jia*, Lei Chen and Peng-Peng Zhang. Cellular and Molecular Basis of
Neurodegeneration in Parkinson Disease. Frontiers in Aging Neuroscience, 2018,10: 109.(IF=4.504)
Jin-Jing Jia?, Xian-Si Zeng?*, Xin-Qiang Song, Peng-Peng Zhang and Lei Chen*. Diabetes Mellitus and Alzheimer's
Disease: The Protection of Epigallocatechin-3-gallate in Streptozotocin Injection-Induced Models. Frontiers in
Pharmacology, 2017, 8: 834(IF=4.4)
Jin-Jing Jia?, Xian-Si Zeng?*, Kun Li, Li-Fang Ma, Lei Chen, Xin-Qiang Song. The expression of thioredoxin-1 in acute
epinephrine stressed mice. Cell Stress and Chaperones, 2016, 21: 935-941.(IF=3.163)
Xian-Si Zeng, Jin-Jing Jia*, Li-Fang Ma. Gensenoside Rb1 protects rat PC12 cells from oxidative stress-induced
endoplasmic reticulum stress: the involvement of thioredoxin-1, Molecular and Cellular Biochemistry, 2015,
410(1-2): 239-246(.(IF=2.613)
Jin-Jing Jia, Xian-Si Zeng, Jing-Mei Zhong, Jie Bai*. The epinephrine increases tyrosine hydroxylase expression
through upregulating thioredoxin-1 in PC12 cells. Biochimie, 2015, 115: 52-58.(IF=3.123)
Jin-Jing Jia?, Xian-Si Zeng?, Xiao-Shuang Zhou, Ye Li, Jie Bai*. The induction of thioredoxin-1 by epinephrine
withdraws stress via interaction with β-arrestin-1. Cell Cycle, 2014, 13(19): 3121-3131. (IF=5.006)
Wen-Li Chen, Xian-Si Zeng, Fu-Cheng Luo, Tao Lv, Xiao-Shuang Zhou, Jie Bai*. The decreased expression of
thioredoxin-1 in brain of mice with experimental autoimmune myasthenia gravis.Neuromuscular Disorders,
2014, 24(8):726-35. (IF=3.464)
Xian-Si Zeng, Jin-Jing Jia, Yongwon Kwon, Sheng-Dong Wang, Jie Bai*. The role of thioredoxin-1 in suppression of
endoplasmic reticulum stress in Parkinson disease. Free Radical Biology and Medicine, 2014, 67:10-18.
(IF=5.271)
Xian-Si Zeng, Xiao-Shuang Zhou, Fu-Cheng Luo, Jin-Jing Jia, Lei Qi, Zhao-Xiang Yang, Wei Zhang , Jie Bai*.
Comparative analysis on neuroprotective effects of ginsenosides Rg1 and Rb1 extracted from Panax
notoginseng against cerebral ischemia. Canadian Journal of Physiology and Pharmacology, 2014, 92:102-108.
(IF=1.556)
Jin-Jing Jia, Xian-Si Zeng, Ye Li, Sha Ma, Jie Bai*. Ephedrine induced thioredoxin-1 expression through β-adrenergic
receptor/cyclic AMP/protein kinase A/dopamine- and cyclic AMP-regulated phosphoprotein signaling
pathway. Cellular Signalling, 2013, 25: 1194-1201. (IF=4.304)
Fu-Cheng Luo, Lu Zhao, Juan Deng, Min Liang, Xian-Si Zeng, Hua Liu, Jie Bai*. Geranylgeranylacetone protects
against morphine-induced hepatic and renal damage in mice. Molecular Medicine Reports, 2013, 7: 694-700.
(IF=1.17)
獲獎(jiǎng)情況
2016年 信陽(yáng)師范學(xué)院優(yōu)秀實(shí)習(xí)指導(dǎo)教師
2017年 信陽(yáng)師范學(xué)院優(yōu)秀教師
