職稱：副教授
學(xué)位：農(nóng)學(xué)博士
專業(yè)：動(dòng)物遺傳育種與繁殖
辦公室：敏思樓505
聯(lián)系方式： weixuefeng.happy@163.com
教育經(jīng)歷
2013-2017 西北農(nóng)林科技大學(xué)動(dòng)物科技學(xué)院，農(nóng)學(xué)博士
2010-2013云南農(nóng)業(yè)大學(xué)動(dòng)物科技學(xué)院，農(nóng)學(xué)碩士
2006-2010湖州師范學(xué)院生命科學(xué)學(xué)院，理學(xué)學(xué)士
工作經(jīng)歷
2017.09- 至今 信陽(yáng)師范學(xué)院 生命科學(xué)學(xué)院 講師
教學(xué)情況
主講課程：本科生課程《遺傳學(xué)》、《實(shí)驗(yàn)動(dòng)物學(xué)》、《生物技術(shù)制藥》，研究生課程《表觀遺傳學(xué)》、《生物發(fā)展史》
研究領(lǐng)域
家畜肌肉組織發(fā)育和脂肪沉積的重要基因挖掘及分子調(diào)控機(jī)理研究，主要關(guān)注肌肉和脂肪相關(guān)功能基因、非編碼RNA miRNA、circRNA功能、互作及調(diào)控機(jī)制。
主持科研項(xiàng)目
主持國(guó)家自然科學(xué)基金青年項(xiàng)目，信陽(yáng)師范學(xué)院高層次人才科研啟動(dòng)基金項(xiàng)目共2項(xiàng)，參與中原科技創(chuàng)新領(lǐng)軍人才項(xiàng)目1項(xiàng)；
1. 國(guó)家自然科學(xué)基金青年項(xiàng)目，“牛CircMYBPC1調(diào)控肌原代細(xì)胞增殖、分化的分子機(jī)制解析”，2019.01-2021.12，27萬，在研，主持。
2. 信陽(yáng)師范學(xué)院高層次人才科研啟動(dòng)基金項(xiàng)目，“長(zhǎng)鏈非編碼RNA調(diào)控牛肌細(xì)胞增殖分化的分子機(jī)制研究”，在研，主持。
發(fā)表論文
1、Xuefeng Wei, Hui Li, Bowen Zhang, ... & Hong Chen*. miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development. RNA Biology, 2016, 13(12): 1300-1309.
2、Xuefeng Wei, Hui Li, Jiameng Yang, ... & Hong Chen*. Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p. Cell Death & Disease. 2017, 8(10): e3153.
3、Xuefeng Wei, Hui Li, Guangwei Zhao, ... & Hong Chen*. ΔFosB regulates rosiglitazone-induced milk fat synthesis and cell survival. Journal of cellular physiology, 2017, 11.20. DOI:10.1002/jcp.26218.
4、Hui Li#, Xuefeng Wei#, Jiameng Yang, ... & Hong Chen*. circFGFR4 Promotes Differentiation of Myoblasts via Binding miR-107 to Relieve Its Inhibition of Wnt3a. Molecular Therapy-Nucleic Acids, 2018, 11: 272-283. (#，co-first)
5、Hui Li#, Xuefeng Wei#, Jiameng Yang, ... & Hong Chen*. Development transcriptome profiling of bovine muscle tissue reveals an aboundant GosB the regulates myoblasts proliferation and apoptosis. Oncotarget, 2017, 8(19):32083-32100.
6、Hui Li#, Jiameng Yang#, Xuefeng Wei#, Chengchuang Song, ... & Hong Chen*. CircFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a. Journal of cellular physiology, 2018, 233(6): 4643-4651.
7、Xuefeng Wei, Shuang Han, Shuzhe Wang ... Yun Ma. ANGPTL8 regulates adipocytes differentiation and adipogenesis in bovine. Gene, 2019, 707: 93-99.
8、Xuefeng Wei, Yunchang Zhu, Jie Du ... Yun Ma. Analysis of ANGPTL8 promoter activity and screening of related transcription factors in bovine. Gene, 2021, 784: 145594.
9、Mengjie Chen,# Xuefeng Wei,# Mingming Song, ... & Hui Li*. Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC. Molecular Therapy-Nucleic Acids, 2021, 24: 352-368. (#，co-first)
10、 Bowen Zhang, Hanfang Cai, Xuefeng Wei, Jiajie Sun, ... & Hong Chen. MiR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. International Journal of Molecular Sciences. 2016, 17(2), 182.
11、 Mingxun Li, Xiaomei Sun, Yang Zhou, Xuefeng Wei, ... & Hong Chen. Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism. Journal of Functional Foods 2015, 18, 492-500.
